CRAM Converter
Convert CRAM files online for free
Drop or upload your .CRAM file
How to convert your CRAM file
- Click Select File above, and choose your CRAM file.
- You'll see a preview.
- Click the "Convert file to..." button to save your file in the format you want.
Convert CRAM to another file type
The converter easily converts your CRAM file to various formats—free and online. No Excel or extra software needed.
- CRAM to BAM
- CRAM to VCF
- CRAM to CSV
- CRAM to JSON
- CRAM to XML
- CRAM to YAML
- CRAM to YML
- CRAM to TOML
- CRAM to INI
- CRAM to CFG
- CRAM to CONF
- CRAM to DAT
Convert a file to CRAM
The converter also works in reverse, allowing you to convert your file into the CRAM file type—in the best quality.
- DBF to CRAM
- XML to CRAM
- SQLITE to CRAM
- XLSX to CRAM
- SQL to CRAM
- TSV to CRAM
- ACCDB to CRAM
- YAML to CRAM
- MDB to CRAM
- CSV to CRAM
- ODS to CRAM
- JSON to CRAM
About CRAM files
CRAM files are a highly efficient format used for storing compressed DNA sequencing reads. As a derivative of BAM, CRAM files are popular in genomics for their reduced storage requirements. However, converting CRAM files to other formats is often necessary for broader compatibility and analysis.
CRAM files can be converted to several formats, including BAM, FASTQ, and SAM. Popular software tools for these conversions include BCFTools and HTSlib, which offer command-line utilities for handling such tasks. For a detailed understanding of CRAM files, you can refer to the Wikipedia article on CRAM.
There are important considerations to keep in mind when converting CRAM files. First, CRAM files compress data by referencing external reference genomes, which must be accessible during conversion. This dependency can complicate the conversion process, especially when specific reference versions are required. Additionally, the large size of genomic data can result in long conversion times and require significant computational resources.
Despite these challenges, many users find CRAM's compression beneficial for storage purposes. However, its complexity can be a drawback, especially for those unfamiliar with bioinformatics tools. This is why using a user-friendly service like Convert.Guru is advantageous. By simply dragging and dropping your CRAM files onto our platform, you can convert them into various formats without the hassle of installing and learning complex software.
Choose Convert.Guru for a seamless and efficient conversion experience, ensuring your genomic data is ready for analysis in the format you need.
The CRAM Converter Story
The history of Convert.Guru began more than 25 years ago in California, when Tom Simondi published the most comprehensive database of file formats on his website. Before that, Tom had worked on Space Shuttle development at the Air Force Systems Command’s Space Division in Los Angeles. He is known as one of the top programmers of the late 1980s.
When Microsoft integrated Tom’s Filext database into Windows XP, it became the leading platform for analyzing and processing file types and formats.
Today, we use the latest technologies to analyze, process, and convert one of the world's largest collections of file formats. We are committed to developing the best CRAM converter by continuously improving quality, usability, and reliability.