Extract text from MXT files
To convert your MXT file to another format, you need MO.Control or other Data software.
To convert other file formats to the "Biophysics Measurement Data" file type, you need software like MO.Control or a similar tool.
The .MXT extension represents two very different, highly specialized file types that often cause confusion.
1. NanoTemper MicroScale Thermophoresis (MST) Data (87% of users):
Most commonly, an .MXT file is a raw data container generated by NanoTemper Technologies instruments (like the Monolith series). These files store binding affinity measurements used in biophysics to study how molecules interact. The problem: These are proprietary binary files locked to the instrument's control software. You cannot open them in Excel, GraphPad Prism, or generic text editors. Researchers often get stuck with .MXT files when they need to analyze data away from the lab computer. To use this data, you must export it to CSV or XLSX using the MO.Affinity Analysis software.
2. ArcGIS Map Template (~3% of users):
In the GIS world, an .MXT file is a layout template for the legacy ArcMap software (part of ArcGIS Desktop). It stores map layouts, toolbars, and basemap settings to ensure consistency across projects. The friction: ArcMap is being retired (March 2026), and modern ArcGIS Pro uses a completely different project structure (.APRX). Old .MXT templates often cannot be opened directly in modern workflows without importing them, and they are useless without the referenced underlying geodatabases (.GDB) or shapefiles.
Convert.Guru analyzes your MXT file, detects the exact format, and lets you read the text inside.
Users also converted MXF, MTX, WKZ, GPX and TTP files.
If you want to convert MXT file to SHP, KML, KMZ, GPX, GEOJSON, TOPOJSON, TIF, TIFF, ECW, SID, IMG or DEM, you can use MO.Control or similar software from the "MicroScale Thermophoresis Data" category. In the File menu, look for Save As… or Export….
To convert LAZ, KMZ, DTM, CSV, DEM, PRJ, LAS, GPX, DSM, SHP, DBF or KML files to MXT, try MO.Control or another comparable tool in the "MicroScale Thermophoresis Data" category.
The history of Convert.Guru began over 25 years ago in California with Tom Simondi’s file-format database. A former contributor to Space Shuttle development and a software pioneer of the 1980s, Simondi established a trusted resource for file type analysis that was even referenced by Microsoft Windows XP. Today, we use modern technology to process and convert thousands of file formats while continually improving our MXT converter.